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QuickView for IL1R1 (gene)


Gene Symbol:
IL1R1 Homo sapiens Homo sapiens
Full name:
interleukin 1 receptor type 1
Synonyms:
CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, interleukin-1 receptor type 1, CD121 antigen-like family member A, IL-1R-1, IL-1RT-1, IL-1RT1, interleukin 1 receptor alpha, type I, interleukin-1 receptor alpha, interleukin-1 receptor type I
Genomic Location:
Chr 2: 102136834-102162766
Description:
This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related c...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2q11.2-q12.1





GO Molecular Function

cytokine binding | interleukin-1, type I, activating receptor activity | transmembrane signaling receptor activity | platelet-derived growth factor receptor binding | enzyme binding | signaling receptor binding | interleukin-1 receptor activity | growth factor binding | interleukin-1 binding | signaling receptor activity | cytokine receptor activity | protein binding | growth factor receptor binding | protease binding

GO Biological Process

positive regulation of immune response | regulation of T cell mediated immunity | positive regulation of locomotion | response to cytokine | response to interleukin-1 | regulation of localization | regulation of immune system process | defense response | interleukin-1, type I, activating receptor activity | positive regulation of cellular component movement | cellular process | regulation of cell motility | positive regulation of immune effector process | positive regulation of adaptive immune response | regulation of response to cytokine stimulus | regulation of immune response | regulation of cellular process | positive regulation of neutrophil migration | regulation of cellular extravasation | positive regulation of interferon-gamma production | positive regulation of T cell cytokine production | response to stimulus | positive regulation of immune system process | response to stress | interleukin-1 receptor activity | positive regulation of response to cytokine stimulus | regulation of signal transduction | positive regulation of T-helper 1 cell cytokine production | positive regulation of neutrophil extravasation | regulation of neutrophil extravasation | regulation of cell migration | interleukin-1-mediated signaling pathway | cytokine-mediated signaling pathway | regulation of cellular component movement | regulation of T cell cytokine production | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of leukocyte migration | positive regulation of cellular extravasation | cytokine receptor activity | cell communication | inflammatory response | regulation of cytokine production involved in immune response | positive regulation of signal transduction | regulation of cytokine-mediated signaling pathway | regulation of locomotion | response to organic substance | regulation of interleukin-1-mediated signaling pathway | cell surface receptor signaling pathway | regulation of neutrophil migration | regulation of adaptive immune response | positive regulation of cytokine production involved in immune response | immune response | positive regulation of T-helper 1 type immune response | positive regulation of leukocyte migration | positive regulation of cytokine production | positive regulation of T cell mediated immunity | positive regulation of cytokine-mediated signaling pathway | regulation of cell communication | signaling | regulation of cytokine production | cellular response to interleukin-1 | regulation of interferon-gamma production | immune system process | positive regulation of interleukin-1-mediated signaling pathway | cellular response to organic substance | positive regulation of cell motility | regulation of inflammatory response | positive regulation of signaling | signal transduction | regulation of signaling

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | plasma membrane | integral component of plasma membrane | extracellular region | cell periphery | cell surface | membrane | intrinsic component of plasma membrane