QuickView for IL7R;jsessionid=9ABE66624E0FA4B446EF1E29163A3648 (gene)

Gene Symbol:

IL7R Homo sapiens

Full name:

interleukin 7 receptor

Synonyms:

CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, interleukin-7 receptor subunit alpha, CD127 antigen, IL-7 receptor subunit alpha, IL-7R subunit alpha, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6

Genomic Location:

Chr 5: 35892748-35912681

Description:

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombinat...

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The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TGANTCA_AP1_C ,  RYTTCCTG_ETS2_B ,  P53_DECAMER_Q2 ,  AML_Q6 ,  STAT6_02 ,  AREB6_04 ,  OSF2_Q6 ,  ETS2_B ,  RACCACAR_AML_Q6 ,  CETS1P54_01 ,  ELK1_01 ,  TTGTTT_FOXO4_01 ,  COREBINDINGFACTOR_Q6 ,  ELF1_Q6

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Cytogenetic Map:

5p13.2

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