QuickView for INTS11 (gene)
- Gene Symbol:
- INTS11
Homo sapiens - Full name:
- integrator complex subunit 11
- Synonyms:
- CPSF3L, CPSF73L, INT11, RC-68, RC68, integrator complex subunit 11, CPSF3-like protein, cleavage and polyadenylation specific factor 3-like, cleavage and polyadenylation-specific factor 3-like protein, protein related to CPSF subunits of 68 kDa, related to CPSF subunits 68 kDa
- Genomic Location:
- Chr 1: 1236828-1249909
- Description:
-
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1p36.33
GO Molecular Function
hydrolase activity | catalytic activity | protein binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | snRNA metabolic process | RNA processing | cellular process | snRNA transcription | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | snRNA transcription by RNA polymerase II | ncRNA 3'-end processing | ncRNA processing | cellular nitrogen compound metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | ncRNA transcription | biosynthetic process | aromatic compound biosynthetic process | snRNA processing | snRNA 3'-end processing | metabolic process | RNA 3'-end processing | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | cellular macromolecule biosynthetic process | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
integrator complex | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | membrane-enclosed lumen | blood microparticle | cytosol | intracellular
