QuickView for ISG15;jsessionid=911526D99B9DCA5D36BD41EF59FD61D4 (gene)

Gene Symbol:

ISG15 Homo sapiens

Full name:

ISG15 ubiquitin-like modifier

Synonyms:

G1P2, IFI15, IMD38, IP17, UCRP, hUCRP, ubiquitin-like protein ISG15, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein, 15 kDa, ubiquitin cross-reactive protein

Genomic Location:

Chr 1: 938742-939782

Description:

The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cel...

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The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  IRF1_01 ,  IRF_Q6 ,  TGCCAAR_NF1_Q6 ,  IRF7_01 ,  ICSBP_Q6 ,  ISRE_01 ,  STTTCRNTTT_IRF_Q6

Cytogenetic Map:

1p36.33

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