QuickView for ITGB3 (gene)

Gene Symbol:

ITGB3 Homo sapiens

Full name:

integrin subunit beta 3

Synonyms:

BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, integrin beta-3, antigen CD61, integrin beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), platelet membrane glycoprotein IIIa

Genomic Location:

Chr 17: 42686207-42745076

Description:

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adh...

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The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  CTCAGGG_MIR125B_MIR125A ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  AGGGCAG_MIR18A ,  TCCAGAG_MIR518C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

17q21.32

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