QuickView for ITSN2;jsessionid=E67AC4A221E7BD3706243AB3FA8CCE97 (gene)

Gene Symbol:

ITSN2 Homo sapiens

Full name:

intersectin 2

Synonyms:

PRO2015, SH3D1B, SH3P18, SWA, SWAP, intersectin-2, SH3 domain-containing protein 1B, SH3P18-like WASP-associated protein

Genomic Location:

Chr 2: 24279239-24436881

Description:

This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis.

This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  GATA1_03 ,  TCANNTGAY_SREBP1_01 ,  CTATGCA_MIR153 ,  ATGTACA_MIR493 ,  CTTTGA_LEF1_Q2 ,  E2A_Q2 ,  RYCACNNRNNRNCAG_UNKNOWN ,  ACTGTGA_MIR27A_MIR27B ,  DBP_Q6 ,  TGCAAAC_MIR452 ,  CAGGTG_E12_Q6 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  PXR_Q2 ,  GGGCGGR_SP1_Q6 ,  ATACTGT_MIR144 ,  PTF1BETA_Q6 ,  GTGCCTT_MIR506 ,  AP2REP_01 ,  MYOGENIN_Q6 ,  DR4_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-421 ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-493-5p

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Cytogenetic Map:

2p23.3

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