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QuickView for Isoetharine (compound)
PubChem
| Name: | Isoetharine |
|---|---|
| PubChem Compound ID: | 23702 |
| Description: | Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma. |
| Molecular formula: | C14H25NO6S |
| Molecular weight: | 335.417 g/mol |
| Synonyms: |
1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)-butyl)-, methanesulfonate (salt); 4-(1-HYDROXY-2-[(1-METHYLETHYL)AMINO]BUTYL)-1,2-BENZENEDIOL METHANESULFONATE SALT; MLS000069674; 3,4-Dihydroxy-alpha-(1-(isopropylamino)propyl)benzyl alcohol methanesulfonate (salt); 7279-75-6; EU-0100671; Isoetarine mesilate; Isoetharine mesylate salt; Isoetharine mesylate [USAN:BAN]; EINECS 230-695-8.
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DrugBank
Identification
| Name: | Isoetharine |
|---|---|
| Name (isomeric): | DB00221 |
| Drug Type: | small molecule |
| Description: | Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma. |
| Synonyms: |
Isoetharine mesylate; Isoetarinum [INN-Latin]; Isoetharine Hcl; Isoetarina [INN-Spanish]
|
| Brand: | Neoisuprel, Bronkometer, Bronkosol, Dey-Lute Isoetharine, Isoetarine, Dilabron, Etyprenaline, Isoetharine HCl S/F, Isoetarin, Beta-2 |
| Category: | Adrenergic beta-Agonists, Bronchodilator Agents |
| CAS number: | 530-08-5 |
Pharmacology
| Indication: | For the treatment of asthma, wheezing, and chronic asthmatic bronchitis. |
|---|---|
| Pharmacology: | Isoetharine is a relatively selective beta2-adrenergic bronchodilator. Isoetharine is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. Adrenergic bronchodilators are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs. |
| Mechanism of Action: |
The pharmacologic effects of isoetharine are attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediato...
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| Toxicity: | Signs of overdose include tachycardia, palpitations, nausea, headache, and epinephrine-like side effects. |
| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
