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QuickView for Isoproterenol (compound)
PubChem
| Name: | Isoproterenol |
|---|---|
| PubChem Compound ID: | 13701 |
| Description: | Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. |
| Molecular formula: | C11H18ClNO3 |
| Molecular weight: | 247.718 g/mol |
| Synonyms: |
Isoproterenol hydrochloride; 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, hydrochloride, (R)- (9CI); (-)-Isoprenaline hydrochloride; l-Isoprenaline chloride; (R)-Isoprenaline hydrochloride; (R)-Isoproterenol hydrochloride; 949-36-0; Benzyl alcohol, 3,4-dihydroxy-alpha-((isopropylamino)methyl)-, hydrochloride, (-)-; BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)-, HYDROCHLORIDE, (-; BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)-, HYDROCHLORIDE, (+.
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DrugBank
Identification
| Name: | Isoproterenol |
|---|---|
| Name (isomeric): | DB01064 |
| Drug Type: | small molecule |
| Description: | Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. |
| Synonyms: |
Isoprenalin; Isoprenaline; Epinephrine Isopropyl Homolog; Isoproterenol Chloride; Isopropylarterenol; Isopropylnoradrenaline; L-Isoproterenol; Isopropylnorepinephrine; L-Isopropylnoradrenaline; N-Isopropylnorepinephrine.
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| Brand: | Euspiran, Isonorin, Aleudrin, Bronkephrine, Medihaler-Iso, Novodrin, Respifral, Aludrin, Neodrenal, Isupren, Norisodrine, Isuprel, Isadrine, Isorenin, Saventrine, Assiprenol, Aerolone, Aleudrine, Norisodrine Aerotrol, Isonorene, Asiprenol, Aludrine, Proternol, Asmalar, Vapo-Iso, Bellasthman, Isuprel Mistometer, Neo-Epinine |
| Category: | Sympathomimetic, Adrenergic beta-Agonists, Cardiotonic Agents, Sympathomimetics, Bronchodilator Agents |
| CAS number: | 7683-59-2 |
Pharmacology
| Indication: | For the treatment of mild or transient episodes of heart block that do not require electric shock or pacemaker therapy also used in management of asthma and chronic bronchitis |
|---|---|
| Pharmacology: |
Isoproterenol is a relatively selective beta2-adrenergic bronchodilator. Isoproterenol is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. The pharmacologic effects of beta adrenergic agonist drugs, including Isoproterenol, are at least in part attributable to stimulation through beta adrenergic recept...
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| Mechanism of Action: |
The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of...
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| Route of elimination: | Excretion following inhalation administration is primarily renal and the major metabolite is the sulfate conjugate of isoproterenol. |
| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
Enzymes
