QuickView for JAG2 (gene)

Gene Symbol:

JAG2 Homo sapiens

Full name:

jagged 2

Synonyms:

HJ2, SER2, protein jagged-2

Genomic Location:

Chr 14: 104679121-104706206

Description:

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcrip...

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The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTTGTAT_MIR381 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GTTTGTT_MIR495 ,  GGGCGGR_SP1_Q6 ,  GTGCCTT_MIR506

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

14q32.33

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