QuickView for JUN (gene)

Gene Symbol:

JUN Homo sapiens

Full name:

Jun proto-oncogene, AP-1 transcription factor subunit

Synonyms:

AP-1, AP1, c-Jun, p39, transcription factor AP-1, Jun activation domain binding protein, activator protein 1, enhancer-binding protein AP1, jun oncogene, proto-oncogene c-Jun, v-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog

Genomic Location:

Chr 1: 59019051-59022373

Description:

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions i...

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This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACTGTAG_MIR139 ,  ALX4_01 ,  GATA1_03 ,  MAZ_Q6 ,  GATA_Q6 ,  GATA_C ,  YTATTTTNR_MEF2_02 ,  CEBP_Q2_01 ,  CAGTGTT_MIR141_MIR200A ,  ATGTACA_MIR493 ,  AMEF2_Q6 ,  GATAAGR_GATA_C ,  CTAWWWATA_RSRFC4_Q2 ,  GATA1_04 ,  WHN_B ,  TAAWWATAG_RSRFC4_Q2 ,  CTTTGTA_MIR524 ,  GGGAGGRR_MAZ_Q6 ,  MEF2_02 ,  GGGNRMNNYCAT_UNKNOWN ,  TGAYRTCA_ATF3_Q6 ,  CEBPDELTA_Q6 ,  RGAANNTTC_HSF1_01 ,  MEF2_01 ,  HSF1_01 ,  CCAWYNNGAAR_UNKNOWN ,  GTTTGTT_MIR495 ,  ATF3_Q6 ,  GGGCGGR_SP1_Q6 ,  HSF2_01 ,  GATA1_02 ,  HMEF2_Q6 ,  STAT_01 ,  WCTCNATGGY_UNKNOWN ,  CEBP_Q3 ,  MTF1_Q4 ,  AACATTC_MIR4093P ,  CEBP_C ,  GTCNYYATGR_UNKNOWN ,  GATA1_05 ,  MEF2_03 ,  IK1_01 ,  AAAGGAT_MIR501 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  ACCATTT_MIR522 ,  CREB_Q2_01 ,  GGGTGGRR_PAX4_03 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-362 ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-495

miRNA binding sites
(Source: miRecords):

hsa-miR-15a/hsa-miR-16 Targeted Genes

Cytogenetic Map:

1p32.1

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