Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for Junctophilin 2 (gene)


Gene Symbol:
JPH2 Homo sapiens Homo sapiens
Full name:
junctophilin 2
Synonyms:
CMH17, JP-2, JP2, junctophilin-2, junctophilin type 2
Genomic Location:
Chr 20: 42173751-42249632
Description:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Pan troglodytes Danio rerio Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 20
20q13.12





GO Molecular Function

ligand-gated calcium channel activity | phosphatidylinositol-4,5-bisphosphate binding | modified amino acid binding | passive transmembrane transporter activity | transmembrane transporter activity | lipid binding | ligand-gated ion channel activity | ion gated channel activity | phospholipid binding | phosphatidylinositol-3-phosphate binding | anion binding | phosphatidylinositol bisphosphate binding | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | phosphatidylinositol-3,4,5-trisphosphate binding | calcium-release channel activity | protein binding | phosphatidylserine binding | metal ion transmembrane transporter activity | phosphatidylinositol binding | phosphatidylinositol-4-phosphate binding | phosphatidylinositol-3,5-bisphosphate binding | cation channel activity | inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | channel activity | calcium channel activity | ion channel activity | phosphatidic acid binding | substrate-specific channel activity | phosphatidylinositol-5-phosphate binding | phosphatidylinositol phosphate binding

GO Biological Process

positive regulation of release of sequestered calcium ion into cytosol | positive regulation of ion transmembrane transporter activity | regulation of cellular localization | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | ligand-gated calcium channel activity | establishment of localization | negative regulation of cellular process | cellular chemical homeostasis | positive regulation of cation channel activity | cellular process | localization | cellular homeostasis | regulation of calcium-mediated signaling | passive transmembrane transporter activity | metal ion transport | regulation of striated muscle tissue development | establishment of localization in cell | regulation of cellular process | positive regulation of ryanodine-sensitive calcium-release channel activity | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | ligand-gated ion channel activity | calcium ion homeostasis | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | positive regulation of cation transmembrane transport | cellular localization | divalent metal ion transport | metal ion homeostasis | regulation of calcium ion transport into cytosol | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | calcium ion transmembrane transport | ion transmembrane transport | cation transmembrane transporter activity | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | positive regulation of intracellular signal transduction | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | positive regulation of calcium-mediated signaling | regulation of release of sequestered calcium ion into cytosol | negative regulation of sequestering of calcium ion | regulation of calcium ion transmembrane transport | cation homeostasis | cellular cation homeostasis | cell communication | positive regulation of transporter activity | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | calcium-release channel activity | positive regulation of transport | positive regulation of molecular function | release of sequestered calcium ion into cytosol | calcium-mediated signaling | regulation of ryanodine-sensitive calcium-release channel activity | cation transmembrane transport | regulation of cardiac muscle tissue development | metal ion transmembrane transporter activity | regulation of intracellular signal transduction | chemical homeostasis | calcium ion transport | regulation of sequestering of calcium ion | positive regulation of ion transport | ion homeostasis | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | regulation of cell communication | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | cation transport | channel activity | positive regulation of calcium ion transport into cytosol | regulation of developmental process | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | regulation of transport | regulation of cation channel activity | cellular metal ion homeostasis | ion channel activity | regulation of calcium ion transmembrane transporter activity | ion transport | divalent inorganic cation homeostasis | substrate-specific channel activity | positive regulation of calcium ion transport | positive regulation of signaling | signal transduction | regulation of signaling | regulation of muscle organ development

GO Cellular Component

supramolecular fiber | integral component of membrane | sarcoplasmic reticulum | intracellular membrane-bounded organelle | organelle membrane | sarcomere | cell | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | endoplasmic reticulum | junctional sarcoplasmic reticulum membrane | contractile fiber | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | junctional membrane complex | membrane-bounded organelle | sarcoplasmic reticulum membrane | organelle | I band | sarcoplasm | cell periphery | Z disc | intracellular | membrane | supramolecular complex