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QuickView for KA1 (gene)


Gene Symbol:
GRIK4 Homo sapiens Homo sapiens
Full name:
glutamate ionotropic receptor kainate type subunit 4
Synonyms:
EAA1, GRIK, GluK4, KA1, glutamate receptor ionotropic, kainate 4, excitatory amino acid receptor 1, glutamate receptor KA1, glutamate receptor, ionotropic, kainate 4
Genomic Location:
Chr 11: 120036238-120362179
Description:
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring io...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q23.3





GO Molecular Function

transmitter-gated ion channel activity | neurotransmitter receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | kainate selective glutamate receptor activity | cation transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | glutamate receptor activity | potassium channel activity | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | potassium ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | establishment of localization | cellular process | localization | passive transmembrane transporter activity | metal ion transport | chemical synaptic transmission | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | ion gated channel activity | modulation of chemical synaptic transmission | cell-cell signaling | ion transmembrane transport | synaptic signaling | kainate selective glutamate receptor activity | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | cellular potassium ion transport | ion transmembrane transporter activity | potassium ion transport | synaptic transmission, glutamatergic | extracellular ligand-gated ion channel activity | cell communication | cation transmembrane transport | potassium channel activity | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | cell surface receptor signaling pathway | potassium ion transmembrane transporter activity | sodium ion transmembrane transport | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | sodium channel activity | cation channel activity | regulation of cell communication | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | cation transport | channel activity | glutamate receptor signaling pathway | potassium ion transmembrane transport | ion channel activity | ion transport | ionotropic glutamate receptor signaling pathway | substrate-specific channel activity | signal transduction | regulation of signaling

GO Cellular Component

presynaptic membrane | integral component of membrane | synapse | potassium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | receptor complex | presynapse | protein-containing complex | postsynaptic membrane | postsynapse | plasma membrane | kainate selective glutamate receptor complex | integral component of plasma membrane | sodium channel complex | cell periphery | ionotropic glutamate receptor complex | transmembrane transporter complex | cation channel complex | ion channel complex | cell junction | membrane | intrinsic component of plasma membrane