QuickView for KCNAB2 (gene)

Gene Symbol:

KCNAB2 Homo sapiens

Full name:

potassium voltage-gated channel subfamily A regulatory beta subunit 2

Synonyms:

AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, KCNA2B, KV-BETA-2, voltage-gated potassium channel subunit beta-2, K(+) channel subunit beta-2, potassium channel, voltage gated subfamily A regulatory beta subunit 2, potassium voltage-gated channel, shaker-related subfamily, beta member 2

Genomic Location:

Chr 1: 6008967-6083110

Description:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume....

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ETS_Q4 ,  RYTTCCTG_ETS2_B ,  PEA3_Q6 ,  GGGYGTGNY_UNKNOWN ,  CAGGTG_E12_Q6 ,  NRF2_01 ,  P300_01 ,  ETS1_B

Cytogenetic Map:

1p36.31

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