QuickView for KCNE1 (gene)

Gene Symbol:

KCNE1 Homo sapiens

Full name:

potassium voltage-gated channel subfamily E regulatory subunit 1

Synonyms:

ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK, potassium voltage-gated channel subfamily E member 1, IKs producing slow voltage-gated potassium channel subunit beta Mink, cardiac delayed rectifier potassium channel protein, delayed rectifier potassium channel subunit IsK, minimal potassium channel, potassium channel, voltage gated subfamily E regulatory beta subunit 1, potassium voltage-gated channel, Isk-related family, member 1, potassium voltage-gated channel, Isk-related subfamily, member 1, voltage gated potassiun channel accessory subunit

Genomic Location:

Chr 21: 34740858-34806443

Description:

The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the del...

View Full Description

The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

EFC_Q6 ,  AAAGACA_MIR511 ,  TTGTTT_FOXO4_01 ,  ACAWYAAAG_UNKNOWN

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

21q22.12

search → result