QuickView for KCNE3;jsessionid=92271347B9F0B06840E10B1EA524794E (gene)

Gene Symbol:

KCNE3 Homo sapiens

Full name:

potassium voltage-gated channel subfamily E regulatory subunit 3

Synonyms:

HOKPP, HYPP, MiRP2, potassium voltage-gated channel subfamily E member 3, cardiac voltage-gated potassium channel accessory subunit, minK-related peptide 2, minimum potassium ion channel-related peptide 2, potassium channel subunit beta MiRP2, potassium channel, voltage gated subfamily E regulatory beta subunit 3, potassium voltage-gated channel, Isk-related family, member 3, voltage-gated K+ channel subunit MIRP2

Genomic Location:

Chr 11: 73843534-73856248

Description:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume....

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP4_01 ,  CEBPB_02 ,  CP2_02

Cytogenetic Map:

11q13.4

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