QuickView for KCNK3 (gene)

Gene Symbol:

KCNK3 Homo sapiens

Full name:

potassium two pore domain channel subfamily K member 3

Synonyms:

K2p3.1, OAT1, PPH4, TASK, TASK-1, TBAK1, potassium channel subfamily K member 3, TWIK-related acid-sensitive K(+) channel 1, TWIK-related acid-sensitive K+ channel, acid-sensitive potassium channel protein TASK, acid-sensitive potassium channel protein TASK-1, cardiac potassium channel, potassium channel, two pore domain subfamily K, member 3, potassium inwardly-rectifying channel, subfamily K, member 3, two P domain potassium channel, two pore K(+) channel KT3.1, two pore potassium channel KT3.1

Genomic Location:

Chr 2: 26769123-26806222

Description:

This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the ...

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This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  DR3_Q4 ,  GATA3_01 ,  GATA_Q6 ,  GATA_C ,  SRF_Q6 ,  ZIC3_01 ,  GGGYGTGNY_UNKNOWN ,  TATA_C ,  AP2_Q6_01 ,  SRF_Q4 ,  LMO2COM_02 ,  TGCCAAR_NF1_Q6 ,  GATA1_02 ,  AATGTGA_MIR23A_MIR23B ,  ZIC2_01 ,  SRF_Q5_01 ,  CCAWWNAAGG_SRF_Q4 ,  SRF_C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323

Cytogenetic Map:

2p23.3

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