QuickView for KIF18A;jsessionid=DF3FB09F3D48514796170E68146687DE (gene)
- Gene Symbol:
- KIF18A
Homo sapiens - Full name:
- kinesin family member 18A
- Synonyms:
- MS-KIF18A, PPP1R99, kinesin-like protein KIF18A, protein phosphatase 1, regulatory subunit 99
- Genomic Location:
- Chr 11: 27998739-28086322
- Description:
-
KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
11p14.1
GO Molecular Function
actin binding | ribonucleotide binding | nucleotide binding | microtubule motor activity | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | ATP-dependent microtubule motor activity, plus-end-directed | catalytic activity | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | motor activity | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ATP-dependent microtubule motor activity | ion binding | microtubule plus-end binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | tubulin-dependent ATPase activity | hydrolase activity, acting on acid anhydrides | microtubule binding | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
antigen processing and presentation | developmental process involved in reproduction | gonad development | establishment of localization | response to hormone | microtubule cytoskeleton organization | male gamete generation | male meiotic nuclear division | regulation of organelle organization | microtubule-based process | cellular process | establishment of organelle localization | localization | protein transport | reproductive system development | response to estradiol | multicellular organismal reproductive process | macromolecule localization | establishment of localization in cell | gamete generation | regulation of cellular process | cellular response to lipid | organelle localization | cellular component organization | establishment of chromosome localization | development of primary sexual characteristics | response to stimulus | chromosome segregation | supramolecular fiber organization | microtubule-based movement | reproduction | cellular localization | antigen processing and presentation of exogenous peptide antigen via MHC class II | cellular response to organic cyclic compound | cellular response to hormone stimulus | system development | reproductive process | antigen processing and presentation of peptide antigen via MHC class II | multicellular organism development | retrograde vesicle-mediated transport, Golgi to ER | sister chromatid segregation | seminiferous tubule development | organic substance transport | response to lipid | cell cycle | mitotic metaphase plate congression | peptide transport | vesicle-mediated transport | metaphase plate congression | microtubule depolymerization | nuclear chromosome segregation | cellular protein complex disassembly | Golgi vesicle transport | regulation of microtubule-based process | multicellular organism reproduction | antigen processing and presentation of exogenous antigen | development of primary male sexual characteristics | response to organic substance | male sex differentiation | anatomical structure development | mitotic cell cycle | nuclear division | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | male gonad development | amide transport | animal organ development | cytoskeleton organization | protein depolymerization | mitotic nuclear division | establishment of protein localization | microtubule polymerization or depolymerization | cellular response to estradiol stimulus | meiotic cell cycle | response to organic cyclic compound | protein localization | protein-containing complex disassembly | reproductive structure development | developmental process | organelle organization | tube development | antigen processing and presentation of peptide antigen | chromosome organization | immune system process | cellular response to organic substance | sex differentiation | mitotic sister chromatid segregation | sexual reproduction | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of cytoskeleton organization | multicellular organismal process
GO Cellular Component
mitotic spindle midzone | supramolecular fiber | chromosome | intracellular membrane-bounded organelle | ruffle | microtubule associated complex | microtubule organizing center | chromosome, centromeric region | mitotic spindle astral microtubule | cell | kinetochore | microtubule | cytoplasm | cytoplasmic microtubule | spindle | intracellular organelle | membrane microdomain | kinetochore microtubule | kinesin complex | protein-containing complex | cell projection | plasma membrane | cell leading edge | membrane raft | aster | microtubule cytoskeleton | spindle microtubule | spindle midzone | membrane-bounded organelle | nucleus | organelle | cell periphery | plasma membrane raft | astral microtubule | cytosol | cytoskeleton | intracellular | mitotic spindle | caveola | membrane | supramolecular complex
