QuickView for KIF3B;jsessionid=546F649770729EDEECC87F580F6DE192 (gene)
- Gene Symbol:
- KIF3B
Homo sapiens - Full name:
- kinesin family member 3B
- Synonyms:
- FLA8, HH0048, KLP-11, kinesin-like protein KIF3B, microtubule plus end-directed kinesin motor 3B
- Genomic Location:
- Chr 20: 30329128-30386475
- Description:
-
The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of m...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-127 , Predicted Gene Targets for miR-143 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-93 , Predicted Gene Targets for miR-137 , Predicted Gene Targets for miR-29 , Predicted Gene Targets for miR-496
- Cytogenetic Map:
-
20q11.21
GO Molecular Function
GTPase binding | Rho GTPase binding | enzyme binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | microtubule motor activity | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | ATP-dependent microtubule motor activity, plus-end-directed | Ras GTPase binding | catalytic activity | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | motor activity | nucleoside-triphosphatase activity | ATPase activity, coupled | intraciliary transport particle B binding | purine nucleotide binding | ATP-dependent microtubule motor activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | small GTPase binding | microtubule binding | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
regulation of cell cycle process | microtubule-based transport | microtubule cytoskeleton organization involved in mitosis | antigen processing and presentation | establishment of localization | microtubule cytoskeleton organization | vesicle cytoskeletal trafficking | intracellular transport | microtubule-based process | pattern specification process | cellular process | establishment of organelle localization | centrosome separation | localization | determination of left/right symmetry | microtubule organizing center organization | regulation of cell cycle | positive regulation of cell division | spindle assembly | establishment of localization in cell | positive regulation of cytokinesis | cytoskeleton-dependent intracellular transport | plus-end-directed organelle transport along microtubule | regulation of cellular process | organelle localization | cellular component organization | regulation of cell division | mitotic spindle organization | organelle transport along microtubule | microtubule-based movement | cellular localization | antigen processing and presentation of exogenous peptide antigen via MHC class II | cellular component assembly | organelle assembly | antigen processing and presentation of peptide antigen via MHC class II | multicellular organism development | retrograde vesicle-mediated transport, Golgi to ER | positive regulation of cell cycle | determination of bilateral symmetry | cell cycle | cell projection assembly | vesicle-mediated transport | establishment of vesicle localization | mitotic centrosome separation | regulation of cytokinesis | anterograde axonal transport | intraciliary transport | protein-containing complex localization | Golgi vesicle transport | intraciliary transport involved in cilium assembly | antigen processing and presentation of exogenous antigen | centrosome cycle | anatomical structure development | plus-end-directed vesicle transport along microtubule | mitotic cell cycle | nuclear division | cell projection organization | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | transport along microtubule | cilium assembly | cytoskeleton organization | mitotic nuclear division | cilium organization | axo-dendritic transport | developmental process | organelle organization | positive regulation of cell cycle process | vesicle transport along microtubule | antigen processing and presentation of peptide antigen | mitotic spindle assembly | vesicle localization | immune system process | spindle organization | axonal transport | multicellular organismal process
GO Cellular Component
supramolecular fiber | neuron projection | microtubule associated complex | microtubule organizing center | cell | microtubule | cytoplasm | spindle | intracellular organelle | kinesin II complex | centrosome | kinesin complex | protein-containing complex | cell projection | plasma membrane bounded cell projection cytoplasm | midbody | cilium | vesicle | plus-end kinesin complex | extracellular exosome | microtubule cytoskeleton | cytoplasmic region | spindle microtubule | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | axon cytoplasm | extracellular space | axon | cytosol | cytoskeleton | ciliary tip | intracellular | membrane | supramolecular complex
