QuickView for KPNA3;jsessionid=14068BBD14E9F85F0CC01BA459702EFC (gene)

Gene Symbol:

KPNA3 Homo sapiens

Full name:

karyopherin subunit alpha 3

Synonyms:

IPOA4, SRP1, SRP1gamma, SRP4, hSRP1, importin subunit alpha-4, SRP1-gamma, importin alpha 4, importin alpha Q2, importin alpha-3, importin subunit alpha-3, karyopherin alpha 3 (importin alpha 4), qip2

Genomic Location:

Chr 13: 49171462-49265058

Description:

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene...

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The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTTGTAT_MIR381 ,  IRF1_01 ,  TTTGCAC_MIR19A_MIR19B ,  TTTGCAG_MIR518A2 ,  AAGCCAT_MIR135A_MIR135B ,  RSRFC4_01 ,  TTTTGAG_MIR373 ,  CATTGTYY_SOX9_B1 ,  AACTGAC_MIR223 ,  CTTTGCA_MIR527 ,  RSRFC4_Q2 ,  CAGTGTT_MIR141_MIR200A ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  AMEF2_Q6 ,  ACTGTGA_MIR27A_MIR27B ,  MEF2_02 ,  OCT1_Q6 ,  TAATGTG_MIR323 ,  CEBP_01 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  AGTCTTA_MIR499 ,  GGGCGGR_SP1_Q6 ,  GTATGAT_MIR154_MIR487 ,  AAGGGAT_MIR188 ,  CEBPB_02 ,  AGGTGCA_MIR500 ,  ACTGCAG_MIR173P ,  CAGTCAC_MIR134 ,  GTGCCTT_MIR506 ,  TTGCCAA_MIR182 ,  CEBP_Q3 ,  CCTGCTG_MIR214 ,  ATATGCA_MIR448 ,  MEF2_03 ,  IRF7_01 ,  IK1_01 ,  CTGAGCC_MIR24 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  TGATTTRY_GFI1_01 ,  TBP_01 ,  ISRE_01 ,  MMEF2_Q6 ,  GTTAAAG_MIR302B ,  CAATGCA_MIR33 ,  CACTTTG_MIR520G_MIR520H ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-134 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-33 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-431 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-188 ,  Predicted Gene Targets for miR-409-5p ,  Predicted Gene Targets for miR-455 ,  Predicted Gene Targets for miR-499 ,  Predicted Gene Targets for miR-500

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Cytogenetic Map:

13q14.2

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