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QuickView for KSRP (gene)


Gene Symbol:
KHSRP Homo sapiens Homo sapiens
Full name:
KH-type splicing regulatory protein
Synonyms:
FBP2, FUBP2, KSRP, far upstream element-binding protein 2, FUSE-binding protein 2, p75
Genomic Location:
Chr 19: 6364115-6375822
Description:
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 19
19p13.3





GO Molecular Function

nucleic acid binding | mRNA binding | DNA binding | AU-rich element binding | organic cyclic compound binding | protein binding | mRNA 3'-UTR AU-rich region binding | mRNA 3'-UTR binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | response to cytokine | RNA processing | establishment of localization | regulation of nitric oxide biosynthetic process | negative regulation of cellular process | cellular process | organic substance catabolic process | localization | macromolecule localization | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | positive regulation of mRNA catabolic process | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | mRNA catabolic process | response to stimulus | RNA splicing | RNA splicing, via transesterification reactions | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | negative regulation of low-density lipoprotein particle clearance | cellular nitrogen compound metabolic process | negative regulation of metabolic process | mRNA metabolic process | negative regulation of nitric oxide biosynthetic process | cellular biosynthetic process | negative regulation of reactive oxygen species biosynthetic process | nucleobase-containing compound catabolic process | regulation of nucleic acid-templated transcription | regulation of neurotransmitter levels | nitrogen compound metabolic process | 3'-UTR-mediated mRNA destabilization | regulation of miRNA metabolic process | regulation of gene expression | organic substance transport | RNA catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of RNA stability | cellular response to cytokine stimulus | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | mRNA transport | establishment of RNA localization | mRNA destabilization | regulation of cellular metabolic process | regulation of protein metabolic process | aromatic compound catabolic process | regulation of RNA metabolic process | response to organic substance | cellular macromolecule catabolic process | nucleobase-containing compound transport | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | regulation of mRNA catabolic process | negative regulation of cellular protein metabolic process | gene expression | RNA destabilization | negative regulation of translation | transcription, DNA-templated | RNA transport | regulation of reactive oxygen species biosynthetic process | negative regulation of protein metabolic process | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of reactive oxygen species metabolic process | ncRNA metabolic process | regulation of low-density lipoprotein particle clearance | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | mRNA processing | cellular response to organic substance | regulation of translation | RNA localization | miRNA metabolic process | negative regulation of reactive oxygen species metabolic process | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | cytoplasmic stress granule | exosome (RNase complex) | cell | nuclear lumen | ribonucleoprotein granule | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | membrane-enclosed lumen | cytosol | intracellular | membrane