QuickView for Kv4.3 (gene)

Gene Symbol:

KCND3 Homo sapiens

Full name:

potassium voltage-gated channel subfamily D member 3

Synonyms:

BRGDA9, KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22, potassium voltage-gated channel subfamily D member 3, potassium channel, voltage gated Shal related subfamily D, member 3, potassium ionic channel Kv4.3, potassium voltage-gated channel long, potassium voltage-gated channel, Shal-related subfamily, member 3, sha1-related potassium channel Kv4.3, voltage-gated K+ channel, voltage-gated potassium channel subunit Kv4.3

Genomic Location:

Chr 1: 112119977-112333300

Description:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume....

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  MYOD_Q6_01 ,  MAZR_01 ,  YTATTTTNR_MEF2_02 ,  ZF5_01 ,  PAX8_01 ,  TGACCTY_ERR1_Q2 ,  CAGGTA_AREB6_01 ,  CCTGTGA_MIR513 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  STAT5A_03 ,  E2F1_Q3_01 ,  RNGTGGGC_UNKNOWN ,  WTTGKCTG_UNKNOWN ,  E2F_Q2 ,  AACTTT_UNKNOWN ,  DR4_Q2 ,  ETF_Q6 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-148

Cytogenetic Map:

1p13.2

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