Name: | Calcium Channels, L-Type |
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Description: | Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites. |
Synonyms: |
VDCC, L-Type; L Type Voltage Dependent Calcium Channels; L Type Calcium Channels; Calcium Channels, L Type; L-Type Voltage-Dependent Calcium Channels; L-Type Calcium Channel; Long Lasting Calcium Channels; Long-Lasting Calcium Channels; Calcium Channel, L-Type; L Type VDCC.
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