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QuickView for LDH1;jsessionid=CAFC32CA0FAB380C771D130471378638;jsessionid=F31903EF253159C835BDB3791338986B;jsessionid=E418BE70A08A69EEE0D26690B017270B;jsessionid=29F7452FC4EA38A367928C76BD612ABA (gene)


Gene Symbol:
Ldha Mus musculus Mus musculus
Full name:
lactate dehydrogenase A
Synonyms:
Ldh1, Ldhm, l7R2, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-M, M-LDH, lactate dehydrogenase 1, A chain, lactate dehydrogenase A4
Genomic Location:
Chr 7: 54102583-54110996
Description:
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to hemolytic anemia and early postimplantation death in mice. Mult...
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_010699
NM_001136069
NR_102727
Protein Names
Q564E2
P06151
G5E8N5
A0A1B0GSX0



GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | lactate dehydrogenase activity | catalytic activity | L-lactate dehydrogenase activity | protein binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity

GO Biological Process

response to extracellular stimulus | purine ribonucleotide metabolic process | oxidoreductase activity, acting on CH-OH group of donors | nucleoside phosphate catabolic process | lactate biosynthetic process | glucose metabolic process | cellular response to extracellular stimulus | generation of precursor metabolites and energy | organophosphate catabolic process | lactate dehydrogenase activity | cellular process | organic substance catabolic process | glycolytic fermentation | nucleotide metabolic process | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | carbohydrate catabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | purine nucleotide metabolic process | monocarboxylic acid metabolic process | lactate biosynthetic process from pyruvate | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | organic hydroxy compound metabolic process | NADH metabolic process | fermentation | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | monosaccharide metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | L-lactate dehydrogenase activity | biosynthetic process | pyruvate metabolic process | aromatic compound biosynthetic process | carbohydrate metabolic process | nucleotide catabolic process | phosphate-containing compound metabolic process | cell communication | aromatic compound catabolic process | drug metabolic process | carboxylic acid metabolic process | nucleoside diphosphate metabolic process | metabolic process | hexose metabolic process | oxidation-reduction process | glucose catabolic process to lactate via pyruvate | nucleobase-containing compound metabolic process | organic substance metabolic process | lactate metabolic process | ADP metabolic process | organic acid metabolic process | glucose catabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | energy derivation by oxidation of organic compounds | nicotinamide nucleotide metabolic process | NAD metabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | ATP metabolic process | oxidoreductase activity

GO Cellular Component

sperm flagellum | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | 9+2 motile cilium | motile cilium | cell projection | cilium | mitochondrion | membrane-bounded organelle | organelle | sperm fibrous sheath | cytosol | intracellular