QuickView for LIPT1 (gene)

Gene Symbol:

LIPT1 Homo sapiens

Full name:

lipoyltransferase 1

Synonyms:

LIPT1D, lipoyltransferase 1, mitochondrial, lipoate biosynthesis protein, lipoyl ligase

Genomic Location:

Chr 2: 99137850-99146043

Description:

The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudoge...

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The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

2q11.2

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