Correlation Engine 2.0
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QuickView for LOX1 (gene)

Gene Symbol:
OLR1 Homo sapiens Homo sapiens
Full name:
oxidized low density lipoprotein receptor 1
CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, oxidized low-density lipoprotein receptor 1, C-type lectin domain family 8 member A, hLOX-1, lectin-type oxidized LDL receptor 1, ox LDL receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, scavenger receptor class E, member 1
Genomic Location:
Chr 12: 10202166-10216057
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a r...
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12

GO Molecular Function

identical protein binding | carbohydrate binding | protein binding

GO Biological Process

exocytosis | cell motility | neutrophil activation | proteolysis | establishment of localization | defense response | cellular process | secretion | leukocyte degranulation | localization | leukocyte activation | response to stimulus | neutrophil degranulation | response to stress | leukocyte activation involved in immune response | secretion by cell | blood circulation | leukocyte migration | locomotion | nitrogen compound metabolic process | cell migration | leukocyte mediated immunity | vesicle-mediated transport | regulated exocytosis | inflammatory response | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | protein metabolic process | metabolic process | cell adhesion | immune response | organic substance metabolic process | cell activation | neutrophil mediated immunity | immune system process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

secretory granule | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | nuclear lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | secretory granule membrane | protein-containing complex | secretory vesicle | endomembrane system | nucleoplasm | plasma membrane | membrane raft | vesicle | specific granule | integral component of plasma membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | vesicle membrane | cell periphery | membrane-enclosed lumen | tertiary granule membrane | intracellular vesicle | intracellular | specific granule membrane | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane