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QuickView for LRG1 (gene)


Gene Symbol:
LRG1 Homo sapiens Homo sapiens
Full name:
leucine rich alpha-2-glycoprotein 1
Synonyms:
HMFT1766, LRG, leucine-rich alpha-2-glycoprotein, 1300008B03Rik, 2310031E04Rik, leucine rich alpha 2 glycoprotein
Genomic Location:
Chr 19: 4488227-4491036
Description:
The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19p13.3


Transcripts Names
NM_052972
Protein Names
Q68CK4
Q96QZ4
Q8N4F5
P02750



GO Molecular Function

transforming growth factor beta receptor binding | signaling receptor binding | cytokine receptor binding | protein binding

GO Biological Process

exocytosis | neutrophil activation | establishment of localization | regulation of transforming growth factor beta receptor signaling pathway | positive regulation of developmental process | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of endothelial cell proliferation | cellular process | secretion | leukocyte degranulation | localization | brown fat cell differentiation | regulation of angiogenesis | regulation of cellular process | leukocyte activation | regulation of vasculature development | response to stimulus | neutrophil degranulation | leukocyte activation involved in immune response | regulation of cell proliferation | secretion by cell | response to external biotic stimulus | regulation of signal transduction | leukocyte mediated immunity | vesicle-mediated transport | fat cell differentiation | regulated exocytosis | response to bacterium | cell activation involved in immune response | myeloid cell activation involved in immune response | positive regulation of signal transduction | neutrophil activation involved in immune response | positive regulation of cell proliferation | regulation of cellular response to growth factor stimulus | immune response | regulation of endothelial cell proliferation | cell activation | positive regulation of transforming growth factor beta receptor signaling pathway | regulation of cell communication | regulation of epithelial cell proliferation | response to biotic stimulus | regulation of developmental process | developmental process | neutrophil mediated immunity | immune system process | positive regulation of angiogenesis | response to other organism | positive regulation of signaling | regulation of signaling

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | tertiary granule | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | ficolin-1-rich granule lumen | secretory vesicle | endomembrane system | vesicle | extracellular exosome | specific granule | extracellular region | membrane-bounded organelle | extracellular vesicle | specific granule lumen | organelle | extracellular space | tertiary granule lumen | membrane-enclosed lumen | secretory granule lumen | intracellular vesicle | intracellular | membrane | vesicle lumen