QuickView for LRP1B;jsessionid=6491F9A340308A3D4F4AAB5E86001C19 (gene)

Gene Symbol:

LRP1B Homo sapiens

Full name:

LDL receptor related protein 1B

Synonyms:

LRP-1B, LRP-DIT, LRPDIT, low-density lipoprotein receptor-related protein 1B, LRP-deleted in tumors, low density lipoprotein receptor related protein-deleted in tumor, low density lipoprotein receptor-related protein 1B, low density lipoprotein-related protein 1B (deleted in tumors)

Genomic Location:

Chr 2: 140705466-142605740

Description:

This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer.

This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GTATTAT_MIR3693P ,  TGANTCA_AP1_C ,  FOXJ2_02 ,  TGANNYRGCA_TCF11MAFG_01 ,  E4BP4_01 ,  ACTTTAT_MIR1425P ,  WHN_B ,  CREB_Q3 ,  CTTTGTA_MIR524 ,  AGCATTA_MIR155 ,  NFE2_01 ,  AP1_Q6_01 ,  TCTGATA_MIR361 ,  GCTTGAA_MIR498 ,  AP1_01 ,  AP1FJ_Q2 ,  ATGCTGC_MIR103_MIR107 ,  ACTACCT_MIR196A_MIR196B ,  ATGTTTC_MIR494 ,  YKACATTT_UNKNOWN ,  NKX25_02 ,  NRF2_Q4 ,  AP1_Q4 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CTGCAGY_UNKNOWN ,  TGCTTTG_MIR330 ,  AP1_Q2 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  ACCATTT_MIR522 ,  TATTATA_MIR374 ,  TCF11MAFG_01 ,  TGASTMAGC_NFE2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-196 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-361 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

2q22.1-q22.2

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