QuickView for LTC4S (gene)

Gene Symbol:

LTC4S Homo sapiens

Full name:

leukotriene C4 synthase

Synonyms:

leukotriene C4 synthase, LTC4 synthase

Genomic Location:

Chr 5: 179153592-179156119

Description:

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid...

View Full Description

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  RYTTCCTG_ETS2_B ,  STAT6_02 ,  CAGGTG_E12_Q6 ,  TTCYRGAA_UNKNOWN ,  RGAGGAARY_PU1_Q6

Cytogenetic Map:

5q35.3

search → result