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QuickView for LepRb (gene)


Gene Symbol:
Lepr Mus musculus Mus musculus
Full name:
leptin receptor
Synonyms:
LEPROT, Leprb, Modb1, OB-RGRP, Obr, db, diabetes, obese-like, obl, leptin receptor, B219, LEP-R, OB receptor, leptin receptor gene-related protein
Genomic Location:
Chr 4: 101390044-101487910
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

cytokine binding | peptide binding | peptide hormone binding | transmembrane signaling receptor activity | leptin receptor activity | amide binding | signaling receptor activity | identical protein binding | cytokine receptor activity | hormone binding | protein binding | protein-hormone receptor activity

GO Biological Process

positive regulation of insulin secretion involved in cellular response to glucose stimulus | response to cytokine | regulation of cellular localization | regulation of localization | regulation of carbohydrate metabolic process | establishment of localization | regulation of autophagy | response to hormone | negative regulation of cellular process | cell differentiation | organ growth | glucose homeostasis | positive regulation of phosphate metabolic process | regulation of peptide hormone secretion | positive regulation of protein secretion | blood vessel morphogenesis | regulation of bone remodeling | sterol metabolic process | cellular process | lymphocyte differentiation | localization | developmental growth | negative regulation of gluconeogenesis | immune system development | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of behavior | regulation of cellular process | leukocyte activation | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | T cell activation | regulation of peptide secretion | response to stimulus | vasculature development | regulation of feeding behavior | positive regulation of cold-induced thermogenesis | regulation of insulin secretion | positive regulation of protein metabolic process | negative regulation of circadian rhythm | alcohol metabolic process | multicellular organismal homeostasis | tube morphogenesis | negative regulation of eating behavior | reproduction | cardiovascular system development | positive regulation of hormone secretion | regulation of protein transport | negative regulation of metabolic process | hemopoiesis | regulation of peptide transport | blood vessel development | positive regulation of peptide secretion | leukocyte differentiation | organic hydroxy compound metabolic process | leptin receptor activity | cellular response to hormone stimulus | system development | reproductive process | regulation of signal transduction | multicellular organism development | negative regulation of catalytic activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of insulin secretion involved in cellular response to glucose stimulus | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of secretion | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | small molecule metabolic process | cytokine-mediated signaling pathway | bone growth | positive regulation of intracellular signal transduction | vesicle-mediated transport | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | eating behavior | angiogenesis | leptin-mediated signaling pathway | negative regulation of autophagy | cytokine receptor activity | energy homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of establishment of protein localization | regulation of protein phosphorylation | positive regulation of transport | positive regulation of peptide hormone secretion | lymphocyte activation | T cell differentiation | negative regulation of carbohydrate metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | negative regulation of behavior | regulation of eating behavior | positive regulation of insulin secretion | import into cell | regulation of intracellular signal transduction | response to leptin | anatomical structure development | cell surface receptor signaling pathway | regulation of glucose metabolic process | metabolic process | negative regulation of feeding behavior | cholesterol metabolic process | regulation of tissue remodeling | chemical homeostasis | endocytosis | regulation of secretion | behavior | organic substance metabolic process | negative regulation of biosynthetic process | animal organ development | regulation of protein secretion | regulation of phosphate metabolic process | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | anatomical structure formation involved in morphogenesis | steroid metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of locomotor rhythm | signaling | feeding behavior | positive regulation of phosphorylation | anatomical structure morphogenesis | regulation of circadian rhythm | developmental process | tube development | regulation of transport | negative regulation of hydrolase activity | regulation of gluconeogenesis | positive regulation of metabolic process | immune system process | hematopoietic or lymphoid organ development | regulation of locomotor rhythm | cellular response to organic substance | regulation of protein localization | circulatory system development | carbohydrate homeostasis | sexual reproduction | phagocytosis | positive regulation of signaling | signal transduction | cellular response to leptin stimulus | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | cell surface | membrane | intrinsic component of plasma membrane