Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for Lercanidipine (compound)

Name: lercanidipine
PubChem Compound ID: 157917
Molecular formula: C36H42ClN3O6
Molecular weight: 648.188 g/mol
132866-11-6; Lercadip; Lercan; Carmen; Lercaton; Lerdip; 2-((3,3-diphenylpropyl)methylamino)-1,1-dimethylethyl methyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate monohydrochloride; Lercapin; R 75; Cardiovasc.
show more »
Name: lercanidipine
Name (isomeric): DB00528
Drug Type: small molecule
Brand: Lercanidipine [INN]
Category: Calcium Channel Blockers, Antihypertensive Agents
CAS number: 100427-26-7
Indication: For the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
Lercanidipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Lercanidipine is similar to other peripheral vasodilators. Lercanidipine inhibits the influx of extra cellular calcium across the myocardi...
show more »
Mechanism of Action:
By deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, Lercanidipine inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes The decrease in intracellular calcium inhibits the contractile processes of the...
show more »
Affected organisms: Humans and other mammals
Drug interaction:
QuinupristinThis combination presents an increased risk of toxicity