QuickView for Lim2 (gene)

Gene Symbol:

LIM2 Homo sapiens

Full name:

lens intrinsic membrane protein 2

Synonyms:

CTRCT19, MP17, MP19, lens fiber membrane intrinsic protein, MP18, MP20, lens intrinsic membrane protein 2, 19kDa

Genomic Location:

Chr 19: 56574976-56583009

Description:

This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spl...

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This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PBX1_01 ,  SOX5_01 ,  CP2_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23

Cytogenetic Map:

19q13.41

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