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QuickView for Lin7a (gene)


Gene Symbol:
LIN7A Homo sapiens Homo sapiens
Full name:
lin-7 homolog A, crumbs cell polarity complex component
Synonyms:
LIN-7A, LIN7, MALS-1, MALS1, TIP-33, VELI1, protein lin-7 homolog A, mammalian lin-seven protein 1, tax interaction protein 33, vertebrate LIN7 homolog 1
Genomic Location:
Chr 12: 79715302-79855825
Description:
The protein encoded by this gene is involved in generating and maintaining the asymmetric distribution of channels and receptors at the cell membrane. The encoded protein also is required for the localization of some specific channels and can be part of a protein complex that couples synaptic vesicle exocytosis to cell adhesion in the brain.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12
12q21.31





GO Molecular Function

protein domain specific binding | protein binding | L27 domain binding

GO Biological Process

exocytosis | neurotransmitter secretion | protein localization to cell periphery | protein localization to basolateral plasma membrane | establishment of localization | intracellular transport | cellular process | secretion | establishment of organelle localization | localization | protein transport | chemical synaptic transmission | macromolecule localization | establishment of localization in cell | organelle localization | cellular component organization | cellular localization | secretion by cell | cellular component assembly | cell-cell signaling | regulation of neurotransmitter levels | system development | multicellular organism development | protein localization to membrane | organic substance transport | synaptic signaling | peptide transport | vesicle-mediated transport | establishment of vesicle localization | sensory organ development | cell communication | inner ear development | protein-containing complex assembly | anatomical structure development | cellular protein localization | ear development | amide transport | animal organ development | establishment of protein localization | signaling | synaptic vesicle localization | protein localization | cellular macromolecule localization | developmental process | neurotransmitter transport | signal release | vesicle localization | synaptic vesicle transport | multicellular organismal process

GO Cellular Component

occluding junction | synapse | neuron projection | adherens junction | cell | plasma membrane protein complex | synaptic membrane | MPP7-DLG1-LIN7 complex | presynapse | cell-cell junction | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | vesicle | postsynaptic density | extracellular exosome | asymmetric synapse | extracellular region | membrane-bounded organelle | extracellular vesicle | apical junction complex | organelle | postsynaptic specialization | extracellular space | cell periphery | bicellular tight junction | basolateral plasma membrane | intracellular | cell junction | membrane