QuickView for Ltbr (gene)

Gene Symbol:

LTBR Homo sapiens

Full name:

lymphotoxin beta receptor

Synonyms:

CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3, tumor necrosis factor receptor superfamily member 3, lymphotoxin B receptor, lymphotoxin beta receptor (TNFR superfamily, member 3), tumor necrosis factor C receptor, tumor necrosis factor receptor 2-related protein, tumor necrosis factor receptor type III

Genomic Location:

Chr 12: 6363618-6370993

Description:

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed ...

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This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ETS_Q4 ,  RYTTCCTG_ETS2_B ,  ARNT_01 ,  MYC_Q2 ,  CACGTG_MYC_Q2 ,  PEA3_Q6 ,  TEL2_Q6 ,  ARNT_02 ,  GGGAGGRR_MAZ_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  GGGCGGR_SP1_Q6 ,  USF_C ,  MGGAAGTG_GABP_B ,  USF_Q6_01 ,  USF2_Q6 ,  P300_01

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Cytogenetic Map:

12p13.31

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