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QuickView for MAFF;jsessionid=17A10C3D9CF63FBAF317BC9A0C0DD6E2 (gene)


Gene Symbol:
MAFF Homo sapiens Homo sapiens
Full name:
MAF bZIP transcription factor F
Synonyms:
U-MAF, hMafF, transcription factor MafF, v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
Genomic Location:
Chr 22: 36927944-36942460
Description:
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregn...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 22
22q13.1





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | muscle tissue development | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | positive regulation of cellular biosynthetic process | cellular process | hemostasis | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cell differentiation | muscle structure development | skeletal muscle organ development | regulation of cellular process | parturition | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | response to stress | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of epithelial cell differentiation | reproduction | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | blood coagulation | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | wound healing | regulation of gene expression | regulation of epidermis development | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | chordate embryonic development | striated muscle tissue development | regulation of cellular metabolic process | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | coagulation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to wounding | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | regulation of body fluid levels | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | skeletal muscle cell differentiation | regulation of epidermal cell differentiation | muscle organ development | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular