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QuickView for MAGEA2;jsessionid=C8BB72DE11DA1CF226F1046FAE493A3C (gene)


Gene Symbol:
MAGEA2 Homo sapiens Homo sapiens
Full name:
MAGE family member A2
Synonyms:
CT1.2, MAGE2, MAGEA2A, melanoma-associated antigen 2, MAGE-2 antigen, cancer/testis antigen 1.2, cancer/testis antigen family 1, member 2, melanoma antigen 2, melanoma antigen family A, 2, melanoma antigen family A2
Genomic Location:
Chr X: 151669044-151673020
Description:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional control...
Orthologs:
Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr X
Xq28





GO Molecular Function

repressing transcription factor binding | enzyme binding | ubiquitin-like protein ligase binding | protein binding | transcription factor binding | ubiquitin protein ligase binding | histone deacetylase binding

GO Biological Process

RNA metabolic process | intracellular signal transduction | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cellular process | organic substance catabolic process | regulation of ubiquitin-protein transferase activity | negative regulation of nucleic acid-templated transcription | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | regulation of protein ubiquitination | cellular protein catabolic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of catalytic activity | regulation of gene expression | cellular response to stress | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | regulation of protein sumoylation | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | cell aging | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | cellular macromolecule catabolic process | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | transcription, DNA-templated | negative regulation of protein metabolic process | negative regulation of protein sumoylation | organonitrogen compound catabolic process | cellular senescence | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | developmental process | negative regulation of transcription by RNA polymerase II | negative regulation of protein acetylation | heterocycle metabolic process | positive regulation of ubiquitin-protein transferase activity | positive regulation of metabolic process | cellular metabolic process | signal transduction by p53 class mediator | aging | positive regulation of protein ubiquitination | signal transduction | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nuclear body | PML body | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular