QuickView for MAK;jsessionid=8E8467861A29FAD7876B36D2404E7646 (gene)

Gene Symbol:

MAK Homo sapiens

Full name:

male germ cell associated kinase

Synonyms:

RP62, serine/threonine-protein kinase MAK, male germ cell-associated kinase retinal-enriched isoform, serine/threonine protein kinase MAK, testicular secretory protein Li 28

Genomic Location:

Chr 6: 10870942-10939096

Description:

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene...

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The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTACTGT_MIR101 ,  ATGTTAA_MIR302C ,  TTGCCAA_MIR182

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

6p24.2

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