QuickView for MAP4K1;jsessionid=58322502BA86313AB0CEA76B6EB3C362 (gene)
- Gene Symbol:
- MAP4K1
Homo sapiens - Full name:
- mitogen-activated protein kinase kinase kinase kinase 1
- Synonyms:
- HPK1, mitogen-activated protein kinase kinase kinase kinase 1, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1, hematopoietic progenitor kinase 1
- Genomic Location:
- Chr 19: 43770121-43800483
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
ETS_Q4 , RYTTCCTG_ETS2_B , E2F1_Q4_01 , E2F1_Q6_01 , ETS2_B , TGCGCANK_UNKNOWN , GGAANCGGAANY_UNKNOWN , NERF_Q2 , NRF1_Q6 , E2F_Q4_01
- Cytogenetic Map:
-
19q13.2
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | MAP kinase kinase kinase kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of JUN kinase activity | intracellular signal transduction | peptidyl-amino acid modification | regulation of MAP kinase activity | response to drug | positive regulation of phosphate metabolic process | cellular process | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | MAPK cascade | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | JNK cascade | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | activation of MAPKKK activity | protein serine/threonine kinase activity | response to alcohol | positive regulation of protein serine/threonine kinase activity | protein modification process | macromolecule modification | activation of protein kinase activity | stress-activated protein kinase signaling cascade | regulation of cellular response to stress | cellular response to phorbol 13-acetate 12-myristate | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | response to ketone | cellular response to stress | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | protein autophosphorylation | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | cell proliferation | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cellular response to drug | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | positive regulation of molecular function | activation of MAPK activity | protein metabolic process | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | response to antineoplastic agent | regulation of intracellular signal transduction | metabolic process | protein kinase activity | organic substance metabolic process | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of JNK cascade | positive regulation of MAPK cascade | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | positive regulation of phosphorylation | cellular protein metabolic process | positive regulation of MAP kinase activity | kinase activity | peptidyl-serine phosphorylation | cellular protein modification process | positive regulation of JUN kinase activity | MAP kinase kinase kinase kinase activity | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | activation of JUN kinase activity | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
cell | cytoplasm | intracellular | membrane
