QuickView for MAP7;jsessionid=EEB3ED6114D8135F10FC34B3C4D400D2 (gene)

Gene Symbol:

MAP7 Homo sapiens

Full name:

microtubule associated protein 7

Synonyms:

E-MAP-115, EMAP115, ensconsin, MAP-7, dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115)), epithelial microtubule-associated protein of 115 kDa

Genomic Location:

Chr 6: 136705565-136913485

Description:

The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve ...

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The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  E12_Q6 ,  TAL1ALPHAE47_01 ,  ARNT_01 ,  AREB6_02 ,  CACGTG_MYC_Q2 ,  GCANCTGNY_MYOD_Q6 ,  TAGCTTT_MIR9 ,  MYCMAX_02 ,  TAL1BETAE47_01 ,  CAGGTG_E12_Q6 ,  TGCCTTA_MIR124A ,  MYCMAX_01 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  NMYC_01 ,  TTGTTT_FOXO4_01 ,  TAL1BETAITF2_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  TGACATY_UNKNOWN ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  LMO2COM_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u

Cytogenetic Map:

6q23.3

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