Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for MED25 (gene)


Gene Symbol:
MED25 Homo sapiens Homo sapiens
Full name:
mediator complex subunit 25
Synonyms:
ACID1, ARC92, BVSYS, CMT2B2, P78, PTOV2, TCBAP0758, mediator of RNA polymerase II transcription subunit 25, ARC/mediator transcriptional coactivator subunit, activator interaction domain-containing protein 1, activator-recruited cofactor 92 kDa component, mediator of RNA polymerase II transcription, subunit 25 homolog, prostate-derived protein 78 kDa
Genomic Location:
Chr 19: 55013358-55032049
Description:
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth d...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.33





GO Molecular Function

retinoic acid receptor binding | hormone receptor binding | signaling receptor binding | nuclear hormone receptor binding | retinoid X receptor binding | protein binding | transcription factor binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | positive regulation of mediator complex assembly | negative regulation of cellular process | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of chromatin binding | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | positive regulation of cell cycle | regulation of gene expression | regulation of cell cycle arrest | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of protein complex assembly | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | positive regulation of chromatin binding | positive regulation of molecular function | positive regulation of cell cycle arrest | regulation of fibroblast proliferation | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | positive regulation of binding | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of transcription, DNA-templated | negative regulation of fibroblast proliferation | cellular macromolecule biosynthetic process | positive regulation of cell cycle process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular