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QuickView for MED4 (gene)


Gene Symbol:
MED4 Homo sapiens Homo sapiens
Full name:
mediator complex subunit 4
Synonyms:
ARC36, DRIP36, HSPC126, TRAP36, VDRIP, mediator of RNA polymerase II transcription subunit 4, TRAP/SMCC/PC2 subunit p36, activator-recruited cofactor 36 kDa component, mediator, 34-kD subunit, homolog, vitamin D receptor-interacting protein, 36-kD, vitamin D3 receptor-interacting protein complex 36 kDa component
Genomic Location:
Chr 13: 47548093-47567241
Description:
This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 13
13q14.2





GO Molecular Function

hormone receptor binding | signaling receptor binding | thyroid hormone receptor binding | signaling receptor activity | nuclear hormone receptor binding | transcription coactivator activity | protein binding | transcription factor binding | nuclear receptor transcription coactivator activity | transcription coregulator activity | vitamin D receptor binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | response to hormone | androgen receptor signaling pathway | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | steroid hormone mediated signaling pathway | cellular biosynthetic process | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | nitrogen compound metabolic process | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | cell communication | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | response to organic substance | metabolic process | regulation of RNA biosynthetic process | nuclear receptor transcription coactivator activity | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | cellular response to steroid hormone stimulus | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | intracellular receptor signaling pathway | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular macromolecule biosynthetic process | intracellular steroid hormone receptor signaling pathway | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | signal transduction | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | core mediator complex | protein-containing complex | nucleoplasm | mediator complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | membrane