QuickView for MGL1 (gene)

Gene Symbol:

LLGL1 Homo sapiens

Full name:

LLGL1, scribble cell polarity complex component

Synonyms:

DLG4, HUGL, HUGL-1, HUGL1, LLGL, Lgl1, Mgl1, lethal(2) giant larvae protein homolog 1, human homolog to the D-lgl gene protein, lethal giant larvae homolog 1, scribble cell polarity complex component

Genomic Location:

Chr 17: 18069661-18088914

Description:

This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF4ALPHA_Q6 ,  TTGTTT_FOXO4_01 ,  CTTTGT_LEF1_Q2

Cytogenetic Map:

17p11.2

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