QuickView for MIA40 (gene)
- Gene Symbol:
- MIA40
Saccharomyces cerevisiae - Full name:
- Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins
- Synonyms:
- FMP15, MIA40, MIA40, TIM40, YKL195W
- Genomic Location:
- Chr XI: 75826-77037
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | isomerase activity | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor | protein disulfide oxidoreductase activity | catalytic activity | oxidoreductase activity, acting on a sulfur group of donors | iron-sulfur cluster binding | intramolecular oxidoreductase activity | disulfide oxidoreductase activity | protein disulfide isomerase activity | thiol oxidase activity | 2 iron, 2 sulfur cluster binding | oxidoreductase activity
GO Biological Process
protein localization to mitochondrion | establishment of localization | intracellular transport | cellular process | localization | protein transport | protein transmembrane import into intracellular organelle | establishment of protein localization to mitochondrion | protein import into mitochondrial intermembrane space | macromolecule localization | establishment of localization in cell | cellular component organization | intracellular protein transport | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor | protein disulfide oxidoreductase activity | cellular localization | mitochondrion organization | oxidoreductase activity, acting on a sulfur group of donors | organic substance transport | mitochondrial transport | peptide transport | protein localization to organelle | protein import | disulfide oxidoreductase activity | establishment of protein localization to organelle | metabolic process | thiol oxidase activity | oxidation-reduction process | cellular protein localization | amide transport | mitochondrial transmembrane transport | protein folding | establishment of protein localization | transmembrane transport | intracellular protein transmembrane transport | protein localization | cellular macromolecule localization | protein targeting to mitochondrion | organelle organization | protein transmembrane transport | protein targeting | oxidoreductase activity
GO Cellular Component
integral component of organelle membrane | integral component of membrane | mitochondrial intermembrane space | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | integral component of mitochondrial inner membrane | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | intrinsic component of mitochondrial inner membrane | membrane-enclosed lumen | integral component of mitochondrial membrane | mitochondrial membrane | intracellular | membrane
