QuickView for MMP10 (gene)

Gene Symbol:

MMP10 Homo sapiens

Full name:

matrix metallopeptidase 10

Synonyms:

SL-2, STMY2, stromelysin-2, MMP-10, matrix metalloprotease 10, matrix metalloproteinase 10 (stromelysin 2), matrix metalloproteinase-10, transin 2

Genomic Location:

Chr 11: 102146444-102156554

Description:

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encode...

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This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TATAAA_TATA_01 ,  TATA_C ,  TATA_01

Cytogenetic Map:

11q22.2

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