QuickView for MRSA (gene)

Gene Symbol:

SLC9A6 Homo sapiens

Full name:

solute carrier family 9 member A6

Synonyms:

MRSA, NHE6, sodium/hydrogen exchanger 6, Na(+)/H(+) exchanger 6, solute carrier family 9 (sodium/hydrogen exchanger), member 6, solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6

Genomic Location:

Chr X: 134895252-134957094

Description:

This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in mul...

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This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF4ALPHA_Q6 ,  TTTGCAC_MIR19A_MIR19B ,  GATA1_03 ,  ACACTCC_MIR122A ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  CTATGCA_MIR153 ,  SP1_Q4_01 ,  TGCCTTA_MIR124A ,  ACTACCT_MIR196A_MIR196B ,  GGGCGGR_SP1_Q6 ,  CCCNNGGGAR_OLF1_01 ,  CTTTAAR_UNKNOWN ,  SP1_Q6 ,  CTGCAGY_UNKNOWN ,  P300_01 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  TCF1P_Q6 ,  GTTAAAG_MIR302B ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-122a ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-196 ,  Predicted Gene Targets for miR-21 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-488 ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-496

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Cytogenetic Map:

Xq26.3

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