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QuickView for MST1 (gene)


Gene Symbol:
MST1 Homo sapiens Homo sapiens
Full name:
macrophage stimulating 1
Synonyms:
D3F15S2, DNF15S2, HGFL, MSP, NF15S2, hepatocyte growth factor-like protein, hepatocyte growth factor-like protein homolog, macrophage stimulating 1 (hepatocyte growth factor-like), macrophage-stimulating protein
Genomic Location:
Chr 3: 49696391-49701099
Description:
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary mot...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3p21.31





GO Molecular Function

kinase binding | protein kinase binding | receptor tyrosine kinase binding | enzyme binding | signaling receptor binding | hydrolase activity | catalytic activity | serine hydrolase activity | protein tyrosine kinase binding | protein binding | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | peptidase activity

GO Biological Process

regulation of leukocyte chemotaxis | proteolysis | regulation of localization | regulation of carbohydrate metabolic process | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of epithelial cell proliferation | cellular process | regulation of cell motility | negative regulation of gluconeogenesis | regulation of chemotaxis | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | response to stimulus | regulation of cell proliferation | regulation of mammary gland epithelial cell proliferation | positive regulation of mammary gland epithelial cell proliferation | negative regulation of metabolic process | nitrogen compound metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | hepatocyte growth factor receptor signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | regulation of cellular component movement | regulation of cAMP-dependent protein kinase activity | regulation of cellular protein metabolic process | regulation of leukocyte migration | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | negative regulation of carbohydrate metabolic process | protein metabolic process | regulation of kinase activity | cell surface receptor signaling pathway | regulation of glucose metabolic process | metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | serine-type endopeptidase activity | regulation of phosphate metabolic process | serine-type peptidase activity | signaling | endopeptidase activity | regulation of epithelial cell proliferation | regulation of developmental process | regulation of gluconeogenesis | regulation of macrophage chemotaxis | transmembrane receptor protein tyrosine kinase signaling pathway | peptidase activity | signal transduction | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

extracellular region | extracellular space