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QuickView for MTCH1 (gene)


Gene Symbol:
MTCH1 Homo sapiens Homo sapiens
Full name:
mitochondrial carrier 1
Synonyms:
CGI-64, PIG60, PSAP, SLC25A49, mitochondrial carrier homolog 1, cell proliferation-inducing protein 60, presenilin-associated protein, solute carrier family 25, member 49
Genomic Location:
Chr 6: 37043895-37061927
Description:
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 6
6p21.2





GO Molecular Function

protein binding

GO Biological Process

regulation of cysteine-type endopeptidase activity | neuronal ion channel clustering | positive regulation of apoptotic process | regulation of programmed cell death | cell differentiation | nervous system development | neurogenesis | generation of neurons | membrane organization | cellular process | cell maturation | neuron development | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of protein metabolic process | positive regulation of peptidase activity | positive regulation of cysteine-type endopeptidase activity | programmed cell death | positive regulation of proteolysis | apoptotic process | system development | regulation of signal transduction | multicellular organism development | regulation of peptidase activity | regulation of catalytic activity | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of hydrolase activity | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of cellular metabolic process | regulation of protein metabolic process | neuron maturation | positive regulation of molecular function | neuron differentiation | anatomical structure development | activation of cysteine-type endopeptidase activity involved in apoptotic process | developmental maturation | positive regulation of cell death | cell death | positive regulation of programmed cell death | regulation of cell communication | cell development | regulation of endopeptidase activity | developmental process | positive regulation of metabolic process | regulation of cell death | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane