QuickView for MTR;jsessionid=E5CD43FAAD836852FBE2A6E6A3A9F483 (gene)

Gene Symbol:

MTR Homo sapiens

Full name:

5-methyltetrahydrofolate-homocysteine methyltransferase

Synonyms:

HMAG, MS, cblG, methionine synthase, 5-methyltetrahydrofolate-homocysteine methyltransferase 1, cobalamin-dependent methionine synthase, vitamin-B12 dependent methionine synthase

Genomic Location:

Chr 1: 235025341-235130585

Description:

This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript ...

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This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  GGAMTNNNNNTCCY_UNKNOWN ,  TNCATNTCCYR_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  ACTAYRNNNCCCR_UNKNOWN ,  GTGCCTT_MIR506

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a

Cytogenetic Map:

1q43

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