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QuickView for MYH9 (gene)


Gene Symbol:
MYH9 Homo sapiens Homo sapiens
Full name:
myosin heavy chain 9
Synonyms:
BDPLT6, DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHC-IIA, NMMHCA, myosin-9, cellular myosin heavy chain, type A, myosin, heavy chain 9, non-muscle, non-muscle myosin heavy chain 9, non-muscle myosin heavy chain A, non-muscle myosin heavy chain IIa, non-muscle myosin heavy polypeptide 9, nonmuscle myosin heavy chain II-A
Genomic Location:
Chr 22: 35007272-35113927
Description:
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintena...
Orthologs:
Mus musculus Rattus norvegicus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 22
22q12.3





GO Molecular Function

actin binding | ADP binding | actin filament binding | cadherin binding | nucleic acid binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | protein membrane anchor | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | protein domain specific binding | ATP binding | microfilament motor activity | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | motor activity | actin-dependent ATPase activity | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | cell adhesion molecule binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | calmodulin binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | RNA binding

GO Biological Process

membrane protein proteolysis | cell morphogenesis | myoblast fusion | actin filament-based process | cell motility | regulation of cell morphogenesis | proteolysis | phagocytosis, engulfment | syncytium formation by plasma membrane fusion | actin cytoskeleton organization | establishment of localization | blood vessel endothelial cell migration | myeloid cell differentiation | regulation of cell shape | negative regulation of cellular process | integrin-mediated signaling pathway | microtubule cytoskeleton organization | cell differentiation | epithelial cell migration | membrane organization | microtubule-based process | blood vessel morphogenesis | cellular process | establishment of organelle localization | localization | cytokinetic process | protein transport | epithelium migration | immune system development | macromolecule localization | negative regulation of actin filament severing | hemostasis | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | actin filament-based movement | muscle structure development | muscle cell differentiation | regulation of cellular process | leukocyte activation | regulation of metabolic process | organelle localization | positive regulation of cellular protein metabolic process | establishment of cell polarity | cellular component organization | platelet aggregation | T cell activation | positive regulation of protein processing | response to stimulus | vasculature development | positive regulation of protein processing in phagocytic vesicle | positive regulation of protein metabolic process | response to stress | membrane protein ectodomain proteolysis | endothelial cell migration | establishment of spindle localization | tube morphogenesis | reproduction | cellular localization | cardiovascular system development | positive regulation of proteolysis | platelet formation | hemopoiesis | regulation of protein processing | embryo development | blood vessel development | leukocyte migration | blood coagulation | leukocyte differentiation | locomotion | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | cell migration | syncytium formation | spindle localization | wound healing | monocyte differentiation | regulation of gene expression | platelet activation | organic substance transport | cell cycle | platelet morphogenesis | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | peptide transport | vesicle-mediated transport | cell division | regulation of cellular protein metabolic process | meiotic spindle organization | angiogenesis | cytokinesis | actomyosin structure organization | cell morphogenesis involved in differentiation | establishment or maintenance of cell polarity | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | embryo development ending in birth or egg hatching | striated muscle cell differentiation | coagulation | lymphocyte activation | protein metabolic process | response to wounding | import into cell | anatomical structure development | uropod organization | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of body fluid levels | membrane invagination | actin cytoskeleton reorganization | amide transport | endocytosis | cell adhesion | organic substance metabolic process | animal organ development | cytoskeleton organization | establishment of protein localization | cell-cell adhesion | cell activation | anatomical structure formation involved in morphogenesis | meiotic cell cycle | positive regulation of protein maturation | signaling | myotube differentiation | cell development | protein localization | anatomical structure morphogenesis | regulation of developmental process | developmental process | organelle organization | tube development | in utero embryonic development | positive regulation of metabolic process | regulation of actin filament-based process | immune system process | hematopoietic or lymphoid organ development | ameboidal-type cell migration | circulatory system development | spindle organization | establishment of meiotic spindle localization | establishment of T cell polarity | phagocytosis | regulation of cellular component organization | homotypic cell-cell adhesion | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

brush border | cleavage furrow | integral component of membrane | intracellular membrane-bounded organelle | synapse | immunological synapse | ruffle | adherens junction | neuromuscular junction | focal adhesion | actomyosin contractile ring | COP9 signalosome | cell | plasma membrane protein complex | intrinsic component of membrane | integrin complex | cytoplasm | cortical cytoskeleton | spindle | cell-substrate junction | intracellular organelle | actin cytoskeleton | receptor complex | cell-cell adherens junction | cell-cell junction | protein-containing complex | cell projection | contractile ring | plasma membrane | myosin complex | actomyosin | cell leading edge | vesicle | myosin filament | cell trailing edge | extracellular exosome | microtubule cytoskeleton | cytoplasmic region | integral component of plasma membrane | cortical actin cytoskeleton | extracellular region | cell cortex | membrane-bounded organelle | extracellular vesicle | myosin II complex | nucleus | organelle | cell division site | extracellular space | cell periphery | cell-substrate adherens junction | myosin II filament | protein complex involved in cell adhesion | stress fiber | cytosol | cytoskeleton | intracellular | cell junction | actin filament bundle | membrane | uropod | intrinsic component of plasma membrane