QuickView for MYLK3;jsessionid=8E8467861A29FAD7876B36D2404E7646 (gene)

Gene Symbol:

MYLK3 Homo sapiens

Full name:

myosin light chain kinase 3

Synonyms:

MLCK, MLCK2, caMLCK, myosin light chain kinase 3, MLC kinase, cardiac-MLCK, cardiac-MyBP-C associated Ca/CaM kinase, putative myosin light chain kinase 3

Genomic Location:

Chr 16: 45293695-45339722

Description:

Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).

Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGCTGAY_UNKNOWN ,  WGGAATGY_TEF1_Q6

Cytogenetic Map:

16q11.2

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