QuickView for MYOC (gene)

Gene Symbol:

MYOC Homo sapiens

Full name:

myocilin

Synonyms:

GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin, juvenile-onset open-angle glaucoma 1, mutated trabecular meshwork-induced glucocorticoid response protein, myocilin 55 kDa subunit, myocilin trabecular meshwork inducible glucocorticoid response protein, trabecular meshwork inducible glucocorticoid response protein

Genomic Location:

Chr 1: 169871180-169888396

Description:

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intra...

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MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ZIC1_01 ,  TGANNYRGCA_TCF11MAFG_01 ,  ZIC3_01 ,  TATAAA_TATA_01 ,  TGCTGAY_UNKNOWN

Cytogenetic Map:

1q24.3

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